base pair mismatches การใช้

• These methods are simple to run, require standard laboratory technique and equipment and can detect polymorphisms, single base pair mismatches, insertions and deletions at low frequencies.
• These methods are simple to run using standard laboratory techniques and equipment, and can detect polymorphisms, single base pair mismatches, and insertions and deletions at low frequencies.
• The DNA mismatch repair protein PpMSH2 is a central component of the " P . patens " mismatch repair pathway that targets base pair mismatches arising during homologous recombination.
• Many DNA polymerase contain an exonuclease domain, which acts in detecting base pair mismatches and further performs in the removal of the incorrect nucleotide to be replaced by the correct one.
• The error sensing and error correction features, combined with the inherent accuracy that arises from the structure and chemistry of replicative polymerases, contributes to an error rate of approximately 1 base pair mismatch in 10 8 to 10 10 base pairs.